Description

Endo-3-(4-Methylbenzoyl)Bi-Cyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid, Methyl Ester is a specialized bicyclic organic compound that serves as a critical synthetic intermediate in advanced chemical synthesis. Its unique norbornane-based structure with a methylbenzoyl substituent makes it a valuable building block for constructing complex molecular architectures. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents and herbicides with specific stereochemical requirements.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring rigid, bicyclic frameworks.
• Asymmetric Catalysis: Chiral auxiliary or ligand precursor in stereoselective synthesis due to its defined stereochemistry.
• Academic & Industrial R&D: Serves as a model compound in methodological studies for organic synthesis and medicinal chemistry.
• Fine Chemical Production: Intermediate for manufacturing complex fragrance and flavor molecules.

Basic Information

Product Name	Endo-3-(4-Methylbenzoyl)Bi-Cyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid, Methyl Ester
CAS No.	806660-16-2
Molecular Formula	C17H20O3
Molecular Weight	272.34 g/mol
Synonyms	Methyl endo-3-(4-methylbenzoyl)bicyclo[2.2.1]heptane-2-exo-carboxylate; 2-Norbornanecarboxylic acid, 3-(4-methylbenzoyl)-, methyl ester, endo-exo-; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-(4-methylbenzoyl)-, methyl ester, (1R,2S,3R,4S)-rel-; 806660-16-2; Methyl 3-(4-methylbenzoyl)bicyclo[2.2.1]heptane-2-carboxylate; endo-3-(p-Toluoyl)bicyclo[2.2.1]heptane-2-exo-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Endo-3-(4-Methylbenzoyl)Bi-Cyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.