Description

3-(3-Fluoro-5-Nitrophenoxy)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated and nitrated aromatic ether structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and nitro groups can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialized polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design of fluorescent tags or molecular probes for studying biological processes due to its aromatic and electron-withdrawing groups.
• Organic Synthesis Reagent: Acts as a versatile substrate in cross-coupling reactions, nucleophilic aromatic substitution (SNAr), and other catalytic transformations.

Basic Information

Product Name	3-(3-Fluoro-5-Nitrophenoxy)Pyridine
CAS No.	803700-29-0
Molecular Formula	C11H7FN2O3
Molecular Weight	234.19 g/mol
Synonyms	Pyridine, 3-[(3-fluoro-5-nitrophenyl)oxy]-; 3-(3-Fluoro-5-nitrophenoxy)pyridine; 3-[(3-Fluoro-5-nitrophenyl)oxy]pyridine; 3-(3-Fluoro-5-nitro-phenoxy)-pyridine; 5-Nitro-3-fluorophenyl 3-pyridyl ether; 3-Pyridyl 3-fluoro-5-nitrophenyl ether
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-5-Nitrophenoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.