Description

Spiro[Bicyclo[2.2.1]Heptane-2,2-[1,3]Dioxolane]-5-Ethanol, (1S,4R,5R)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its unique spirocyclic and bicyclic fused structure, combined with defined stereochemistry, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional scaffolds.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where its specific stereochemistry can influence biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in enantioselective catalytic reactions.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific stereochemical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including novel cyclization and ring-opening reactions.

Basic Information

Item	Details
Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,2-[1,3]Dioxolane]-5-Ethanol, (1S,4R,5R)- (9Ci)
CAS No.	802911-95-1
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(1S,4R,5R)-5-(Hydroxymethyl)-2,4-dioxaspiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane]; (1S,4R,5R)-Spiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane]-5-ethanol; (1S,4R,5R)-5-(Hydroxymethyl)-2,4-dioxaspiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane]; Chiral Spirocyclic Dioxolane; exo-5-(Hydroxymethyl)-2,4-dioxaspiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane] (stereospecific); Bicyclo[2.2.1]heptane-2-ethanol, 2,2-(1,3-dioxolanyl)-, (1S,4R,5R)-
EINECS	Contact for details

Quality Control

Every batch of Spiro[Bicyclo[2.2.1]Heptane-2,2-[1,3]Dioxolane]-5-Ethanol, (1S,4R,5R)- (9Ci) is produced and tested under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.