Description

(R)-Ethyl 4-(1-Aminoethyl)Benzate CAS NO 802566-87-6 is a chiral, non-natural amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined benzylic amine moiety, enabling the construction of complex molecules with high enantiomeric purity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for developing asymmetric catalysts and auxiliaries used in stereoselective transformations.
• Peptidomimetics & Bioactive Molecule Research: Incorporated into peptide backbones or used to create conformationally constrained analogs for structure-activity relationship (SAR) studies.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-Ethyl 4-(1-Aminoethyl)Benzate
CAS No.	802566-87-6
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(R)-Ethyl 4-(1-Aminoethyl)benzoate; (R)-4-(1-Aminoethyl)benzoic Acid Ethyl Ester; Ethyl (R)-4-(1-Aminoethyl)benzoate; (R)-1-(4-(Ethoxycarbonyl)phenyl)ethan-1-amine; (R)-α-Methyl-4-(ethoxycarbonyl)benzylamine; Benzoic acid, 4-[(1R)-1-aminoethyl]-, ethyl ester; (R)-Ethyl p-(1-aminoethyl)benzoate
EINECS	Contact for details

Quality Control

Our (R)-Ethyl 4-(1-Aminoethyl)Benzate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.