Description

2,8-Diazaspiro[4.5]Decane-1,3-Dione,2,6,8-Trimethyl-(8Ci) is a high-purity, structurally complex spirocyclic organic compound with the CAS number 802557-92-2. This specialized heterocyclic building block is valued for its unique three-dimensional scaffold, which is critical for modulating the physicochemical and biological properties of advanced molecules. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

This compound is primarily utilized as a sophisticated intermediate in research and commercial synthesis. Its applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic structure can contribute to unique modes of action and improved environmental profiles.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes to study biological pathways and protein functions due to its ability to introduce conformational constraint.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and functional materials requiring specific rigid, three-dimensional architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes for complex target molecules.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decane-1,3-Dione,2,6,8-Trimethyl-(8Ci)
CAS No.	802557-92-2
Molecular Formula	C11H18N2O2
Molecular Weight	210.27 g/mol
Synonyms	2,6,8-Trimethyl-2,8-diazaspiro[4.5]decane-1,3-dione; 2,6,8-Trimethyl-1,3-diazaspiro[4.5]decane-2,8-dione; 1,3-Diazaspiro[4.5]decane-1,3-dione, 2,6,8-trimethyl-; 802557-92-2; Spirocyclic dimethyl diazadione; Trimethyl diazaspirodecandione
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decane-1,3-Dione,2,6,8-Trimethyl-(8Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and IR), and impurity profiles are provided with each shipment. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.