Description

8-(3-(Trifluoromethyl)Pyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic and heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and metabolic disorders. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and trifluoromethylpyridine motifs.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with improved efficacy.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of specialty chemicals.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis.

Basic Information

Product Name	8-(3-(Trifluoromethyl)Pyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	801306-54-7
Molecular Formula	C15H17F3N2O2
Molecular Weight	314.31 g/mol
Synonyms	1,4-Dioxa-8-azaspiro[4.5]decane, 8-[3-(trifluoromethyl)-2-pyridinyl]-; 8-(3-(Trifluoromethyl)pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane; 8-(3-Trifluoromethyl-pyridin-2-yl)-1,4-dioxa-8-aza-spiro[4.5]decane; 2-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)pyridine
EINECS	Contact for details

Quality Control

Our 8-(3-(Trifluoromethyl)Pyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.