Description

1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro- is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex pharmaceutical molecules and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science Research: Serves as a precursor for functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-
CAS No.	800401-84-7
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	5-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Chloro-7-azaindole-2-carboxylic acid; 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Chloro-2-carboxy-7-azaindole; 5-Chloro-7-aza-1H-indole-2-carboxylic acid; 5-Chloro-1H-7-azaindole-2-carboxylic acid; 5-Chloro-2-carboxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP and ISO-guided processes for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.