Description

Ethyl 3-(2-Chloro-5-Nitropyridin-4-Yl)-2-Oxopropanoate is a high-value, multi-functional chemical intermediate characterized by its reactive pyridine and oxopropanoate ester structure. This compound is essential for facilitating complex synthetic transformations in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other nitrogen-containing heterocyclic therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its nitro and chloro substituents for further functionalization.
• Chemical Research: Serves as a versatile precursor in academic and industrial laboratories for exploring new organic reactions and synthesizing complex heterocyclic compounds.
• Material Science: Potential intermediate for the development of specialty chemicals, dyes, and functional materials requiring specific pyridine-based scaffolds.

Basic Information

Product Name	Ethyl 3-(2-Chloro-5-Nitropyridin-4-Yl)-2-Oxopropanoate
CAS No.	800401-66-5
Molecular Formula	C₁₀H₉ClN₂O₅
Molecular Weight	272.64 g/mol
Synonyms	Ethyl 3-(2-chloro-5-nitropyridin-4-yl)-2-oxopropanoate; 2-Oxopropanoic acid, 3-(2-chloro-5-nitropyridin-4-yl)-, ethyl ester; Ethyl (2-chloro-5-nitropyridin-4-yl)pyruvate; 4-Pyridinepropanoic acid, 2-chloro-5-nitro-, β-oxo-, ethyl ester; 800401-66-5; Ethyl 2-chloro-5-nitropyridin-4-ylpyruvate
EINECS	Contact for details

Quality Control

Our production of Ethyl 3-(2-Chloro-5-Nitropyridin-4-Yl)-2-Oxopropanoate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.