Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 6-Cyano- is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique fused pyrrolopyridine scaffold, which is integral to the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other small-molecule drug candidates.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic frameworks for medicinal chemistry and material science research.
• Agrochemical Research: Employed in the synthesis of novel active ingredients for crop protection products.
• Biochemical Probe Development: Serves as a core structure for designing molecular probes to study biological pathways and enzyme functions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for exploratory chemistry and method development.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 6-Cyano-
CAS No.	800401-57-4
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	6-Cyano-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 6-Cyanopyrrolo[2,3-b]pyridine-2-carboxylic acid; 2-Carboxy-6-cyano-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 6-cyano-; 800401-57-4; 6-CN-1H-Pyrrolo[2,3-b]pyridine-2-COOH
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 6-Cyano- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.