Description

Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, trans- (9Ci) is a specialized chiral building block featuring a cyclobutane ring system functionalized with a methylthio group. This compound is valued for its unique steric and electronic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclobutane scaffold can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential use as an intermediate for synthesizing complex aroma chemicals with specific stereochemical profiles.
• Material Science Research: Investigated as a monomer or building block for novel polymers with tailored physical properties.
• Academic and Industrial R&D: Employed in methodological studies and process chemistry for constructing strained ring systems.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, trans- (9Ci)
CAS No.	89945-42-6
Molecular Formula	C7H12O2S
Molecular Weight	160.23 g/mol
Synonyms	trans-Methyl 3-(Methylthio)cyclobutanecarboxylate; Methyl trans-3-(Methylsulfanyl)cyclobutanecarboxylate; trans-3-(Methylthio)cyclobutanecarboxylic Acid Methyl Ester; (1r,3r)-3-(Methylsulfanyl)cyclobutanecarboxylic Acid Methyl Ester; (1s,3s)-3-(Methylsulfanyl)cyclobutanecarboxylic Acid Methyl Ester; 3-Methylthiocyclobutanecarboxylic Acid Methyl Ester, trans-; Cyclobutanecarboxylic acid, 3-(methylthio)-, methyl ester, trans-
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 3-(Methylthio)-, Methyl Ester, trans- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. We can tailor specifications to meet the requirements of cGMP, ICH guidelines, or other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.