Description

3-[(tert-Butyldimethylsilyl)Oxy]-1-Propanal is a valuable organosilicon-protected aldehyde intermediate used in advanced organic synthesis. This compound is critical for chemists requiring selective protection and deprotection strategies, particularly in multi-step synthesis of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring hydroxyl group protection.
• Peptide Synthesis: Used in the preparation of peptide analogs and conjugates where the aldehyde functionality is introduced in a protected form.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of functionalized polymers and dendrimers with specific surface properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to form carbon-carbon bonds.
• Asymmetric Synthesis: A chiral precursor or auxiliary in the production of enantiomerically pure compounds for high-value applications.

Basic Information

Item	Details
Product Name	3-[(tert-Butyldimethylsilyl)Oxy]-1-Propanal
CAS No.	89922-82-7
Molecular Formula	C9H20O2Si
Molecular Weight	188.34 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]propanal; 3-(tert-Butyldimethylsilyloxy)propanal; 3-TBDMS-oxypropanal; 3-(TBDMSO)propanal; Propanal, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 3-[(tert-Butyldimethylsilanyl)oxy]-propanal; 3-(tert-Butyldimethylsilyloxy)propionaldehyde
EINECS	Contact for details

Quality Control

Our 3-[(tert-Butyldimethylsilyl)Oxy]-1-Propanal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for research and process-scale applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.