Description

2-Hydroxy-Pent-4-Ynoic Acid Ethyl Ester is a versatile bifunctional chemical intermediate, combining both hydroxyl and alkyne functionalities within an ester framework. This unique structure makes it a valuable synthon for constructing complex molecules in advanced organic synthesis and pharmaceutical research. It is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyne or propargylic alcohol motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Click Chemistry: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Organic Synthesis Reagent: Employed in various carbon-carbon bond-forming reactions, including Sonogashira coupling and other metal-catalyzed processes.
• Flavor & Fragrance Precursor: Used in the synthesis of complex esters and lactones for high-value aroma chemicals.

Basic Information

Product Name	2-Hydroxy-Pent-4-Ynoic Acid Ethyl Ester
CAS No.	89898-34-0
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	Ethyl 2-Hydroxypent-4-ynoate; 4-Pentynoic acid, 2-hydroxy-, ethyl ester; 2-Hydroxy-4-pentynoic acid ethyl ester; Ethyl 2-hydroxy-4-pentynoate; Propargylglycolic acid ethyl ester; Ethyl α-hydroxy-γ-acetylenic butyrate
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-Pent-4-Ynoic Acid Ethyl Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical processes. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.