Description

(E)-Ethyl 3-(2-Fluorophenyl)Acrylate is a high-purity fluorinated acrylate ester building block, essential for advanced organic synthesis. Its core value lies in the strategic incorporation of a fluorine atom and an α,β-unsaturated ester moiety, enabling precise molecular modifications to enhance the properties of target compounds. This intermediate is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom improves biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in the synthesis of high-performance electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated as a functional monomer to introduce fluorinated phenyl groups into specialty polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in Heck reactions and other palladium-catalyzed cross-coupling processes to construct complex, fluorinated biaryl systems.
• Flavor & Fragrance Chemistry: Utilized as a building block for synthesizing novel fluorinated aromatic compounds with unique organoleptic profiles.

Basic Information

Item	Details
Product Name	(E)-Ethyl 3-(2-Fluorophenyl)Acrylate
CAS No.	89760-42-9
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	Ethyl (E)-3-(2-Fluorophenyl)-2-propenoate; trans-Ethyl 3-(2-Fluorophenyl)acrylate; (E)-Ethyl 3-(2-Fluorophenyl)propenoate; 2-Fluorocinnamic Acid Ethyl Ester; Ethyl (E)-2-Fluorocinnamate; Ethyl trans-2-Fluorocinnamate; 3-(2-Fluorophenyl)acrylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of (E)-Ethyl 3-(2-Fluorophenyl)Acrylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material meets stringent internal specifications, with a typical purity of ≥98% (by HPLC). A detailed Certificate of Analysis (COA) documenting assay, isomer purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isomeric Purity ((E)-isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.