Description

2,5-Dichloro-4-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chlorine and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,5-Dichloro-4-(Trifluoromethyl)Pyridine
CAS No.	89719-92-6
Molecular Formula	C6H2Cl2F3N
Molecular Weight	215.99 g/mol
Synonyms	4-(Trifluoromethyl)-2,5-dichloropyridine; 2,5-Dichloro-4-(trifluoromethyl)pyridine; 2,5-Dichloro-4-trifluoromethylpyridine; Pyridine, 2,5-dichloro-4-(trifluoromethyl)-; 2,5-Dichloro-α,α,α-trifluoro-4-picoline
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP requirements for pharmaceutical applications and can provide materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.