Description

3,6-Dichloro-2-(Trifluoromethyl)Pyridine is a high-purity halogenated pyridine derivative, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in the unique reactivity imparted by the chlorine and trifluoromethyl substituents, enabling precise molecular construction. This compound is essential for R&D chemists and process developers in the pharmaceutical and agrochemical industries, where it is used to build complex active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the pyridine core and halogen atoms contribute to biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and electronic chemicals that require fluorinated aromatic systems.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, allowing for versatile functionalization.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	3,6-Dichloro-2-(trifluoromethyl)pyridine
CAS No.	89719-91-5
Molecular Formula	C6H2Cl2F3N
Molecular Weight	215.99 g/mol
Synonyms	2-(Trifluoromethyl)-3,6-dichloropyridine; 3,6-Dichloro-2-trifluoromethylpyridine; 2,5-Dichloro-6-(trifluoromethyl)pyridine; Pyridine, 3,6-dichloro-2-(trifluoromethyl)-; 3,6-Dichloro-α,α,α-trifluoro-2-picoline
EINECS	Contact for details

Quality Control

Every batch of 3,6-Dichloro-2-(trifluoromethyl)pyridine is produced under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.