Description

5-Amino-2-Hydroxy-Nicotinic Acid Methyl Ester is a high-purity, functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, offering both an amino group and a hydroxyl group on the pyridine ring, which enables its use in constructing complex heterocyclic systems. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-infectives, and other bioactive molecules.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Ligand Synthesis: Serves as a precursor for chelating ligands in catalysis and material science applications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and heterocyclic compound research.

Basic Information

Product Name	5-Amino-2-Hydroxy-Nicotinic Acid Methyl Ester
CAS No.	89694-08-6
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	Methyl 5-amino-2-hydroxynicotinate; 2-Hydroxy-5-aminonicotinic acid methyl ester; 5-Amino-2-hydroxy-3-pyridinecarboxylic acid methyl ester; Methyl 5-amino-2-oxo-1,2-dihydropyridine-3-carboxylate; 3-Carbomethoxy-5-amino-2-hydroxypyridine; 5-Amino-2-pyridinol-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Hydroxy-Nicotinic Acid Methyl Ester is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, to ensure traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.