Description

[6As,(+)]-6Aβ,11Aβ-Dihydro-3,9-Dimethoxy-6H-Benzofuro[3,2-C][1]Benzopyran-7-Ol is a high-purity, optically active benzofurobenzopyran derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its complex, fused polycyclic structure makes it a valuable chiral building block or intermediate for developing novel bioactive compounds. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a scaffold or reference standard in structure-activity relationship (SAR) studies and hit-to-lead optimization programs.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Biochemical Research: May be utilized as a ligand or probe in biochemical assays to study enzyme interactions or receptor binding.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of high-value, complex organic molecules for various industrial applications.
• Academic Research: Used in university and institutional laboratories for methodological development in organic synthesis and natural product analog studies.

Basic Information

Product Name	[6As,(+)]-6Aβ,11Aβ-Dihydro-3,9-Dimethoxy-6H-Benzofuro[3,2-C][1]Benzopyran-7-Ol
CAS No.	89647-66-5
Molecular Formula	C₁₉H₁₈O₅
Molecular Weight	326.34 g/mol
Synonyms	(+)-6aβ,11aβ-Dihydro-3,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-7-ol; (6aS,11aS)-3,9-Dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromen-7-ol; (6aS,11aS)-7-Hydroxy-3,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c]chromene; NSC 339587; A benzofurobenzopyran derivative; Optically active benzofurochromene
EINECS	Contact for details

Quality Control

Every batch of [6As,(+)]-6Aβ,11Aβ-Dihydro-3,9-Dimethoxy-6H-Benzofuro[3,2-C][1]Benzopyran-7-Ol is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive characterization by HPLC, NMR, and optical rotation analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+XX° to +XX° (c=1, in solvent)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.