Description

6-Chloro-2,4-Dihydroxy-5-Methyl-3-Nitropyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers requiring a reliable, high-purity intermediate for creating active pharmaceutical ingredients (APIs), specialty chemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those with heterocyclic cores, for therapeutic areas such as antivirals and anti-inflammatories.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its nitro and chloro functional groups for bioactivity.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Serves as an intermediate in the production of specialized dyes and pigments due to its nitropyridine structure.
• Coordination Chemistry: Potential ligand or precursor for metal-organic frameworks (MOFs) and catalysts, utilizing its hydroxyl and nitrogen donor sites.
• Material Science: Building block for advanced polymers or organic electronic materials requiring specific electron-withdrawing or donating properties.

Basic Information

Product Name	6-Chloro-2,4-Dihydroxy-5-Methyl-3-Nitropyridine
CAS No.	89581-70-4
Molecular Formula	C6H5ClN2O4
Molecular Weight	204.57 g/mol
Synonyms	5-Methyl-3-nitro-6-chloropyridine-2,4-diol; 2,4-Dihydroxy-6-chloro-5-methyl-3-nitropyridine; 6-Chloro-5-methyl-3-nitro-2,4-pyridinediol; 3-Nitro-6-chloro-2,4-dihydroxy-5-methylpyridine; 6-Chloro-5-methyl-3-nitropyridine-2,4(1H,3H)-dione (Tautomeric form); CLDHP; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,4-Dihydroxy-5-Methyl-3-Nitropyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material is suitable for demanding applications in GMP-aligned synthesis and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere if possible to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.