Description

3-Nitro-5-(Trifluoromethyl)Pyridine-2-Thiol is a high-value, multi-functional heterocyclic building block characterized by its nitro, trifluoromethyl, and thiol functional groups. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its unique structure enables the introduction of key pharmacophores and agro-active motifs. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine-thiol core.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of drug candidates, particularly in areas targeting enzyme inhibition where the nitro and trifluoromethyl groups are crucial.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of advanced polymers and electronic materials that require specific heterocyclic architectures.
• Chemical Research & Development: A versatile scaffold for organic synthesis, enabling various functionalization reactions due to its reactive thiol and nitro groups.

Basic Information

Product Name	3-Nitro-5-(Trifluoromethyl)Pyridine-2-Thiol
CAS No.	89571-67-5
Molecular Formula	C6H3F3N2O2S
Molecular Weight	224.16 g/mol
Synonyms	2-Mercapto-3-nitro-5-(trifluoromethyl)pyridine; 3-Nitro-5-(trifluoromethyl)-2-pyridinethiol; 5-(Trifluoromethyl)-3-nitropyridine-2-thiol; 2-Pyridinethiol, 3-nitro-5-(trifluoromethyl)-; 3-Nitro-5-trifluoromethylpyridine-2-thiol; 89571-67-5; 3-Nitro-5-(trifluoromethyl)-2-mercaptopyridine
EINECS	Contact for details

Quality Control

Our 3-Nitro-5-(Trifluoromethyl)Pyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.