Description

3-Amino-5-(Trifluoromethyl)Pyridine-2-Thiol is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and thiol substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where it imparts desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Key synthetic intermediate for pharmaceutical active ingredients, particularly in kinase inhibitor and antiviral drug discovery.
• Building block for agrochemicals, including herbicides and fungicides, leveraging the trifluoromethyl group's lipophilicity.
• Precursor in the development of metal-chelating ligands and catalysts for organic synthesis.
• Intermediate for functional dyes and pigments used in advanced material science.
• Starting material for corrosion inhibitors and specialty additives in industrial formulations.
• Research chemical for academic and institutional R&D in medicinal and organic chemistry.

Basic Information

Product Name	3-Amino-5-(Trifluoromethyl)Pyridine-2-Thiol
CAS No.	89571-66-4
Molecular Formula	C6H5F3N2S
Molecular Weight	194.18 g/mol
Synonyms	2-Mercapto-3-amino-5-(trifluoromethyl)pyridine; 3-Amino-5-(trifluoromethyl)-2-pyridinethiol; 5-(Trifluoromethyl)-3-amino-2-pyridinethiol; 2-Pyridinethiol, 3-amino-5-(trifluoromethyl)-; 3-Amino-5-trifluoromethylpyridine-2-thiol; 3-Amino-5-trifluoromethyl-2-mercaptopyridine; 89571-66-4; 3-Amino-5-(trifluoromethyl)-2-mercaptopyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(Trifluoromethyl)Pyridine-2-Thiol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.