Description

3-(Trifluoromethyl)Pyrid-2-Ylhydrazine is a specialized heterocyclic building block featuring a reactive hydrazine group adjacent to a trifluoromethyl-substituted pyridine ring. This unique structure makes it a valuable intermediate for synthesizing advanced pharmaceuticals and agrochemicals, where the introduction of the hydrazine moiety and fluorine atoms can significantly alter biological activity and metabolic stability. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Potential precursor for creating specialized ligands used in catalytic systems or metal-organic frameworks (MOFs).
• Material Science: Intermediate in the synthesis of functionalized polymers or organic electronic materials that require specific nitrogen-containing heterocycles.

Basic Information

Product Name	3-(Trifluoromethyl)Pyrid-2-Ylhydrazine
CAS No.	89570-83-2
Molecular Formula	C6H6F3N3
Molecular Weight	177.13 g/mol
Synonyms	2-Hydrazinyl-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-pyridinylhydrazine; 3-(Trifluoromethyl)pyridine-2-ylhydrazine; 2-Hydrazino-3-trifluoromethylpyridine; 3-Trifluoromethyl-2-hydrazinopyridine; (3-Trifluoromethyl-2-pyridyl)hydrazine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyrid-2-Ylhydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.