Description

[R,(-)]-2-Ethyl-2-Hydroxyvaleric Acid is a high-purity chiral building block and intermediate of significant value in asymmetric synthesis. Its enantiomerically pure structure makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is paramount for product efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereoisomer can enhance activity and reduce environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and R&D: A valuable reagent for research in organic chemistry, medicinal chemistry, and process development within university and corporate laboratories.

Basic Information

Product Name	[R,(-)]-2-Ethyl-2-Hydroxyvaleric Acid
CAS No.	89556-40-1
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(R)-2-Ethyl-2-hydroxyvaleric acid; (R)-(-)-2-Ethyl-2-hydroxyvaleric acid; (2R)-2-Ethyl-2-hydroxypentanoic acid; D-2-Ethyl-2-hydroxyvaleric acid; (R)-2-Hydroxy-2-ethylvaleric acid; (-)-2-Ethyl-2-hydroxyvaleric acid; R-(-)-2-Ethyl-2-hydroxyvaleric acid; 2-Ethyl-2-hydroxyvaleric acid (R-enantiomer)
EINECS	Contact for details

Quality Control

Our [R,(-)]-2-Ethyl-2-Hydroxyvaleric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.