Description

Ethyl 1-Bromocyclopropanecarboxylate is a versatile and highly reactive brominated cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its strained three-membered ring and reactive bromo-ester functionality make it an indispensable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly those containing cyclopropane motifs known for metabolic stability and conformational restriction.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity.
• Material Science Precursor: Employed in the synthesis of specialty monomers and polymers, contributing to materials with unique thermal or mechanical properties.
• Cross-Coupling Reactions: Serves as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Ligand and Catalyst Development: A valuable starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethyl 1-Bromocyclopropanecarboxylate
CAS No.	89544-83-2
Molecular Formula	C6H9BrO2
Molecular Weight	193.04 g/mol
Synonyms	1-Bromocyclopropanecarboxylic Acid Ethyl Ester; Ethyl 1-Bromocyclopropane-1-carboxylate; Cyclopropanecarboxylic acid, 1-bromo-, ethyl ester; 1-Bromo-1-ethoxycarbonylcyclopropane; Ethyl (1-bromocyclopropyl)formate
EINECS	Contact for details

Quality Control

Our Ethyl 1-Bromocyclopropanecarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards expected in fine chemical and pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.