Description

4-Amino-2-Chloro-5-Fluoropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique halogenated and aminated pyridine structure provides a versatile scaffold for constructing complex molecules with targeted biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Amino-2-Chloro-5-Fluoropyridine
CAS No.	89510-90-7
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	2-Chloro-5-fluoro-4-pyridinamine; 5-Fluoro-2-chloro-4-aminopyridine; 4-Amino-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-4-aminopyridine; 4-Pyridinamine, 2-chloro-5-fluoro-; AC-89510907; 89510-90-7 (CAS); 2-Chloro-5-fluoropyridin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-5-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.