Description

5-Bromo-2-Hydroxy-3-Picoline is a halogenated pyridine derivative, a versatile heterocyclic building block prized for its unique reactivity profile. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic and modifiable structure.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-Picoline
CAS No.	89488-30-2
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	5-Bromo-3-methyl-2-pyridinol; 5-Bromo-2-hydroxy-3-methylpyridine; 2-Hydroxy-5-bromo-3-methylpyridine; 3-Methyl-5-bromo-2-pyridone; 5-Bromo-3-methyl-2(1H)-pyridinone; 5-Bromo-2-pyridinol, 3-methyl-; 2-Pyridinol, 5-bromo-3-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-Picoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.