Description

(2S,4S)-2-Methylpiperidin-4-Ol CAS NO 89451-58-1 is a chiral piperidine derivative, a high-value building block in organic synthesis. Its defined stereochemistry and functional groups make it a critical intermediate for constructing complex molecules with precise spatial orientation. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Chemical Research & Development: Employed in academic and industrial R&D for methodological studies in stereoselective synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value, specialty fine chemicals and flavors/fragrances intermediates.

Basic Information

Item	Details
Product Name	(2S,4S)-2-Methylpiperidin-4-Ol
CAS No.	89451-58-1
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(2S,4S)-2-Methyl-4-hydroxypiperidine; (2S,4S)-2-Methyl-4-piperidinol; (2S,4S)-4-Hydroxy-2-methylpiperidine; cis-2-Methyl-4-hydroxypiperidine; (2S,4S)-2-Methylpiperidin-4-ol; 4-Piperidinol, 2-methyl-, (2S,4S)-; 89451-58-1
EINECS	Contact for details

Quality Control

Our (2S,4S)-2-Methylpiperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.