Description

2,3-Difluoro-5-(trifluoromethyl)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring multiple fluorine atoms and a trifluoromethyl group, imparts desirable properties such as enhanced metabolic stability, lipophilicity, and electronic effects to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty chemicals, including liquid crystals, organic semiconductors, and advanced polymers.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, catalysis, and the creation of novel fluorinated compound libraries.

Basic Information

Product Name	2,3-Difluoro-5-(trifluoromethyl)pyridine
CAS No.	89402-42-6
Molecular Formula	C6H2F5N
Molecular Weight	183.08 g/mol
Synonyms	5-(Trifluoromethyl)-2,3-difluoropyridine; 2,3-Difluoro-5-(trifluoromethyl)pyridine; Pyridine, 2,3-difluoro-5-(trifluoromethyl)-; 2,3-Difluoro-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-5-(trifluoromethyl)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.