Description

2-Bromo-3-Fluoro-5-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for synthesizing specialized ligands, catalysts, and functional monomers used in advanced polymers and electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to create complex biaryl structures.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) in medicinal and agrochemical chemistry due to its distinct fluorine substitution pattern.

Basic Information

Product Name	2-Bromo-3-Fluoro-5-(Trifluoromethyl)Pyridine
CAS No.	89402-29-9
Molecular Formula	C6H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	2-Bromo-3-fluoro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-bromo-3-fluoropyridine; 3-Fluoro-2-bromo-5-trifluoromethylpyridine; Pyridine, 2-bromo-3-fluoro-5-(trifluoromethyl)-; 89402-29-9
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.