Description

4-Hydroxypyridine-3-Carboxaldehyde is a versatile heterocyclic aldehyde derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a phenolic hydroxyl group and an aldehyde moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antibacterial agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for creating advanced fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Ligand and Chelator Development: Used to synthesize novel polydentate ligands for catalysis and metal complexation in industrial processes.
• Material Science Precursor: Intermediate in the production of specialty polymers, dyes, and photoactive materials.
• Chemical Research (R&D): Fundamental scaffold in academic and industrial research for heterocyclic chemistry and medicinal chemistry programs.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Hydroxypyridine-3-Carboxaldehyde
CAS No.	89380-70-1
Molecular Formula	C6H5NO2
Molecular Weight	123.11 g/mol
Synonyms	3-Formyl-4-hydroxypyridine; 4-Hydroxy-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 4-hydroxy-; 4-Hydroxynicotinaldehyde; 4-Pyridinol-3-carboxaldehyde; 4(1H)-Pyridone-3-carboxaldehyde (tautomer)
EINECS	Contact for details

Quality Control

Our 4-Hydroxypyridine-3-Carboxaldehyde is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep the container tightly sealed under an inert gas blanket (e.g., nitrogen or argon) to minimize oxidation and moisture uptake. Isolate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.