Description

(Triisopropylsilyl)Acetylene CAS NO 89343-06-6 is a highly versatile organosilicon reagent featuring a terminal alkyne group protected by a bulky triisopropylsilyl (TIPS) moiety. This compound is essential for advanced organic synthesis, particularly in cross-coupling and cycloaddition reactions, where it serves as a robust and selective building block. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially for Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides with tailored biological activity through alkyne-based molecular frameworks.
• Materials Science & Polymer Chemistry: Serves as a monomer or functionalizing agent for creating conductive polymers, dendrimers, and advanced materials with specific optical or electronic properties.
• Organic Synthesis Reagent: A protected acetylene source for Huisgen cycloaddition (click chemistry) and other alkyne transformation reactions in academic and industrial R&D.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of organic semiconductors and light-emitting materials for display and lighting technologies.
• Chemical Biology & Bioconjugation: Facilitates the site-specific labeling of biomolecules (proteins, nucleic acids) via bioorthogonal click chemistry protocols.

Basic Information

Product Name	(Triisopropylsilyl)Acetylene
CAS No.	89343-06-6
Molecular Formula	C11H22Si
Molecular Weight	182.38 g/mol
Synonyms	Triisopropylsilylacetylene; TIPS-Acetylene; 1-(Triisopropylsilyl)ethyne; Ethynyltriisopropylsilane; (Triisopropylsilyl)ethyne; TIPS-C≡CH; Triisopropyl(ethynyl)silane; TIPSA
EINECS	Contact for details

Quality Control

Our (Triisopropylsilyl)Acetylene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.