Description

3-Amino-5-Bromo-4-Chloropyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen and amino functionalities into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core provides essential bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, tags, and linkers in bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Amino-5-Bromo-4-Chloropyridine
CAS No.	89283-92-1
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	5-Bromo-4-chloro-3-pyridinamine; 4-Chloro-5-bromo-3-aminopyridine; 3-Pyridinamine, 5-bromo-4-chloro-; 5-Bromo-4-chloro-3-aminopyridine; 3-Amino-4-chloro-5-bromopyridine; 4-Chloro-5-bromo-pyridin-3-ylamine; 5-Bromo-4-chloropyridin-3-amine
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromo-4-Chloropyridine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, GC, and NMR. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.