Description

1-tert-Butyl 2-Methyl 2,3-Dihydropyridine-1,2(6H)-Dicarboxylate is a high-purity, protected dihydropyridine derivative serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles, which are foundational to numerous active pharmaceutical ingredients (APIs) and specialty chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex nitrogen-containing heterocycles for potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its dihydropyridine core structure.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, including ligands for catalysis and advanced materials.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry for constructing new molecular libraries.
• Process Chemistry: Utilized in route scouting and scale-up studies for the efficient manufacturing of target molecules.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 2,3-Dihydropyridine-1,2(6H)-Dicarboxylate
CAS No.	89227-95-2
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-1,2,3,6-tetrahydropyridine; 1-Boc-2-(methyloxycarbonyl)-1,2,3,6-tetrahydropyridine; 1-tert-Butyl 2-methyl 1,2,3,6-tetrahydropyridine-1,2-dicarboxylate; 2,3-Dihydropyridine-1,2(6H)-dicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester; N-Boc-2-(methoxycarbonyl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydropyridine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester; Boc-2-COOMe-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 2,3-Dihydropyridine-1,2(6H)-Dicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.