Description

(3R)-3α-(4-Hydroxy-3,5-Dimethoxyphenyl)-6α-[4-Hydroxy-3-Methoxyphenyl]-3A,4,6,6Aα-Tetrahydro-1H,3H-Furo[3,4-C]Furan-3Aα-Ol CAS NO 89199-97-3 is a high-purity, complex lignan derivative characterized by its unique furofuran core structure. This compound serves as a critical chiral intermediate and reference standard for advanced pharmaceutical research and development. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on bioactive natural product synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in the development of cardiovascular and neuroprotective agents.
• Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of lignan-based compounds in research and quality control laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the biological activity of modified lignan derivatives.
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total or semi-synthesis of complex natural products containing the furofuran lignan skeleton.
• Biochemical Research: Investigated for its potential interactions with various enzymes and receptors due to its polyphenolic structure.

Basic Information

Product Name	(3R)-3α-(4-Hydroxy-3,5-Dimethoxyphenyl)-6α-[4-Hydroxy-3-Methoxyphenyl]-3A,4,6,6Aα-Tetrahydro-1H,3H-Furo[3,4-C]Furan-3Aα-Ol
CAS No.	89199-97-3
Molecular Formula	C22H24O8
Molecular Weight	416.42 g/mol
Synonyms	(3R,3aR,6S,6aR)-6-(4-Hydroxy-3-methoxyphenyl)-3-(4-hydroxy-3,5-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-ol; (-)-Syringaresinol; Lirioresinol B dimethyl ether; Furofuran Lignan Derivative; Syringaresinol (enantiomer); (3R,3aR,6S,6aR)-Syringaresinol; Tetrahydrofurofuran lignan
EINECS	Contact for details

Quality Control

Our (3R)-3α-(4-Hydroxy-3,5-Dimethoxyphenyl)-6α-[4-Hydroxy-3-Methoxyphenyl]-3A,4,6,6Aα-Tetrahydro-1H,3H-Furo[3,4-C]Furan-3Aα-Ol is produced under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.