Description

1-Bromo-4-(T-Butyldimethylsilyloxy)Butane is a valuable organosilicon-protected bifunctional alkylating agent, primarily used as a key synthetic intermediate in complex organic synthesis. Its molecular structure, featuring a bromoalkyl chain and a robust tert-butyldimethylsilyl (TBDMS) protecting group, makes it essential for constructing specific carbon skeletons with precise functional group control. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity building blocks for developing active pharmaceutical ingredients (APIs), liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used in nucleophilic substitution and coupling reactions to introduce protected hydroxybutyl chains into target molecules.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and display components.
• Polymer & Dendrimer Chemistry: Employed in the controlled synthesis of functionalized polymers, dendrimers, and specialty surfactants.
• Protecting Group Strategy: The TBDMS-protected alcohol functionality allows for selective reactions elsewhere on the molecule, a key tactic in complex molecule assembly.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and plant growth regulators.

Basic Information

Item	Details
Product Name	1-Bromo-4-(T-Butyldimethylsilyloxy)Butane
CAS No.	89043-32-3
Molecular Formula	C10H23BrOSi
Molecular Weight	267.28 g/mol
Synonyms	4-(tert-Butyldimethylsilyloxy)-1-bromobutane; 1-Bromo-4-[(1,1-dimethylethyl)dimethylsilyl]oxybutane; 4-Bromobutyl tert-butyldimethylsilyl ether; 4-(TBDMSO)-1-bromobutane; TBDMS-Protected 4-Bromobutanol; 4-Bromobutoxy-tert-butyldimethylsilane; (4-Bromobutoxy)(tert-butyl)dimethylsilane; 1-Bromo-4-((tert-butyldimethylsilyl)oxy)butane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(T-Butyldimethylsilyloxy)Butane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity while monitoring key impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.