Description

(3-Bromopropoxy)-tert-Butyldimethylsilane is a versatile organosilicon reagent featuring a bromopropyl group protected by a tert-butyldimethylsilyl (TBDMS) ether. This bifunctional molecule is critical for introducing protected hydroxylalkyl linkers in complex organic syntheses, enabling precise molecular construction. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of active pharmaceutical ingredients (APIs), specialty polymers, and functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prodrugs, linker molecules in antibody-drug conjugates (ADCs), and other bioactive compounds.
• Polymer & Material Science: Monomer or functionalization agent for creating silicone-based polymers, surface modifiers, and specialty resins with tailored properties.
• Organic Synthesis Reagent: Used as a protected alkylating agent or a precursor for introducing functionalized propyl chains into target molecules under controlled conditions.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) after functional group manipulation.
• Ligand & Catalyst Development: Building block for synthesizing novel phosphine or nitrogen-based ligands used in homogeneous catalysis.

Basic Information

Product Name	(3-Bromopropoxy)-tert-Butyldimethylsilane
CAS No.	89031-84-5
Molecular Formula	C9H21BrOSi
Molecular Weight	253.26 g/mol
Synonyms	3-Bromopropoxy-tert-butyldimethylsilane; tert-Butyl(3-bromopropoxy)dimethylsilane; 3-Bromo-1-[(tert-butyldimethylsilyl)oxy]propane; 1-Bromo-3-[(tert-butyldimethylsilyl)oxy]propane; (3-Bromopropyloxy)-tert-butyldimethylsilane; TBDMS-3-bromopropyl ether; 3-Bromopropyl TBDMS ether; Silane, (3-bromopropoxy)-tert-butyldimethyl-
EINECS	Contact for details

Quality Control

Our (3-Bromopropoxy)-tert-Butyldimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.