Description

1,1-Dichloro-3-Methyl-1-Trimethylsilyl-2-Hexanol is a specialized organosilicon compound featuring a unique combination of chlorinated and silylated functional groups on a hexanol backbone. This molecular architecture makes it a valuable advanced synthetic intermediate for constructing complex molecules in fine chemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered, silicon-containing motifs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its chlorinated silyl ether structure can contribute to unique biological activity.
• Organosilicon Chemistry: Acts as a versatile precursor for further functionalization, enabling the creation of specialized silanes, siloxanes, and other silicon-based materials.
• Material Science Research: Employed in developing surface modifiers, adhesion promoters, or specialty monomers for advanced polymers and coatings.
• Cross-Coupling Reactions: May be utilized as an electrophilic partner or a protected alcohol precursor in palladium-catalyzed and other metal-mediated coupling reactions.

Basic Information

Product Name	1,1-Dichloro-3-Methyl-1-Trimethylsilyl-2-Hexanol
CAS No.	88920-81-4
Molecular Formula	C10H22Cl2OSi
Molecular Weight	265.27 g/mol
Synonyms	1,1-Dichloro-3-methyl-1-(trimethylsilyl)-2-hexanol; 2-Hexanol, 1,1-dichloro-3-methyl-1-(trimethylsilyl)-; 1-(Trimethylsilyl)-1,1-dichloro-3-methyl-2-hexanol; (1,1-Dichloro-3-methyl-1-trimethylsilyl)hexan-2-ol; TMS-protected dichloro hexanol; Dichloro(trimethylsilyl)hexanol derivative
EINECS	Contact for details

Quality Control

Our production of 1,1-Dichloro-3-Methyl-1-Trimethylsilyl-2-Hexanol adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as identity, assay, and impurity profiles as determined by GC, HPLC, and NMR. We are committed to meeting the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.