Description

Methyl 4-Hydroxybicyclo[2.2.1]heptane-1-carboxylate is a specialized bicyclic organic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique, rigid molecular framework makes it particularly significant for constructing complex molecules with precise stereochemistry. This high-purity intermediate is essential for research and development in the pharmaceutical and fine chemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers into target molecules.
• Fine Chemical Production: Employed in the synthesis of complex fragrances, flavors, and advanced agrochemicals requiring specific three-dimensional structures.
• Academic & Industrial R&D: Serves as a model compound or starting material in methodological development for organic and medicinal chemistry research.
• Material Science: Potential intermediate for synthesizing specialty polymers or liquid crystals with tailored properties derived from its bicyclic core.

Basic Information

Product Name	Methyl 4-Hydroxybicyclo[2.2.1]heptane-1-carboxylate
CAS No.	88888-31-7
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	Methyl 4-hydroxybicyclo[2.2.1]heptane-1-carboxylate; 4-Hydroxybicyclo[2.2.1]heptane-1-carboxylic acid methyl ester; Methyl 4-hydroxy-1-norbornanecarboxylate; 1-Norbornanecarboxylic acid, 4-hydroxy-, methyl ester; Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Hydroxybicyclo[2.2.1]heptane-1-carboxylate is manufactured under strict quality management protocols. We ensure compliance with cGMP standards where applicable, and our rigorous in-process and final release testing includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.