Description

1-(2-Nitro-1-Imidazolyl)-3-Aziridino-2-Propanol is a specialized heterocyclic organic compound featuring both nitroimidazole and aziridine functional groups, which are critical for its biological activity. This compound is valued for its role as a key synthetic intermediate in the development of novel pharmaceuticals and research chemicals. It is primarily sought by R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and advanced synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential radiosensitizers and chemotherapeutic agents targeting hypoxic tumor cells.
• Biochemical Research: Used in academic and industrial laboratories to study DNA alkylation mechanisms and the biochemical pathways of nitroimidazole derivatives.
• Antimicrobial Agent Development: Investigated as a precursor for novel compounds with potential antibacterial and antiprotozoal activities.
• Radiopharmaceuticals: Explored for use in the development of diagnostic imaging agents due to the nitroimidazole moiety's affinity for hypoxic tissues.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce complex heterocyclic structures into target molecules.

Basic Information

Product Name	1-(2-Nitro-1-Imidazolyl)-3-Aziridino-2-Propanol
CAS No.	88876-88-4
Molecular Formula	C8H12N4O3
Molecular Weight	212.21 g/mol
Synonyms	1-(2-Nitroimidazol-1-yl)-3-(aziridin-1-yl)propan-2-ol; 2-Propanol, 1-(2-nitro-1H-imidazol-1-yl)-3-(aziridin-1-yl)-; NSC 380205; 1-(2-Nitro-1-imidazolyl)-3-aziridinopropan-2-ol; Aziridine, 1-[3-hydroxy-2-[(2-nitro-1H-imidazol-1-yl)methyl]ethyl]-; 3-(Aziridin-1-yl)-1-(2-nitro-1H-imidazol-1-yl)propan-2-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Nitro-1-Imidazolyl)-3-Aziridino-2-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.