Description

4-[2-[(1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethyl-4-Oxonaphthalen-1α-Yl]Ethyl]-2(5H)-Furanone is a high-purity, complex organic intermediate featuring a fused decalin and butenolide structure. This compound is valued for its role as a versatile chiral building block in advanced organic synthesis, enabling the construction of intricate molecular architectures. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fragrance sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly for complex natural product derivatives and steroid-like molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and plant growth regulators where specific stereochemistry is critical for bioactivity.
• Fragrance & Flavor Chemistry: Acts as a building block for creating sophisticated musk-like or woody amber fragrance compounds due to its complex polycyclic framework.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials requiring specific rigid, chiral motifs.
• Academic & Process Chemistry: Employed in methodological studies for asymmetric synthesis, total synthesis projects, and catalysis development.

Basic Information

Product Name	4-[2-[(1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethyl-4-Oxonaphthalen-1α-Yl]Ethyl]-2(5H)-Furanone
CAS No.	88862-04-8
Molecular Formula	C20H28O3
Molecular Weight	316.44 g/mol
Synonyms	(1R)-4-[2-(1,4,4aβ,5,6,7,8,8a-Octahydro-2,5,5,8aα-tetramethyl-4-oxonaphthalen-1α-yl)ethyl]-2(5H)-furanone; 4-[2-[(1R)-1,4,4aβ,5,6,7,8,8a-Octahydro-2,5,5,8aα-tetramethyl-4-oxonaphthalen-1α-yl]ethyl]furan-2(5H)-one; (R)-4-(2-(1,4,4aβ,5,6,7,8,8a-Octahydro-2,5,5,8aα-tetramethyl-4-oxonaphthalen-1α-yl)ethyl)dihydrofuran-2(5H)-one; Ambretone precursor; Decalin butenolide derivative.
EINECS	Contact for details

Quality Control

Our production of 4-[2-[(1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethyl-4-Oxonaphthalen-1α-Yl]Ethyl]-2(5H)-Furanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure consistent identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.