Description

Mafosfamide CAS NO 88859-04-5 is a chemically modified prodrug of the active metabolite of the alkylating agent ifosfamide. This compound is of significant interest in pharmaceutical research and development due to its potential as a targeted chemotherapeutic agent. It is primarily utilized by researchers and manufacturers in the pharmaceutical industry for the development of novel oncology treatments and as a key intermediate in the synthesis of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced chemotherapeutic drugs.
• Oncology Research: Used as a reference standard and active compound in preclinical studies for investigating new cancer therapies.
• Prodrug Development: Employed in research focused on designing prodrugs with improved tumor selectivity and reduced systemic toxicity.
• Biochemical Studies: Utilized in laboratory settings to study the mechanisms of action of oxazaphosphorine-based alkylating agents.
• Analytical Standard: Acts as a high-purity standard for quality control and method development in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Mafosfamide
CAS No.	88859-04-5
Molecular Formula	C7H15Cl2N2O3P
Molecular Weight	277.08 g/mol
Synonyms	Mafosfamide; NSC-345842; 4-Hydroxy-ifosfamide mustard; Asta Z 7557; Z-7557; (2-[Bis(2-chloroethyl)amino]-1,3,2-oxazaphosphinan-4-yl)methyl dihydrogen phosphate; Cyclophosphamide mustard phosphate; Ifosfamide mustard phosphate
EINECS	Contact for details

Quality Control

Our Mafosfamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via validated methods such as HPLC and NMR. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.