Description

4-Pentynoicacid,2-Amino-2-Methyl-,Methylester,(2S)-(9Ci) is a chiral, non-proteinogenic amino acid derivative featuring both an alkyne and an ester functional group, making it a versatile and valuable synthetic building block. This compound is specifically engineered for applications requiring high stereochemical purity and reactive handles for further chemical elaboration, such as click chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and advanced molecular probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for incorporating constrained amino acid motifs.
• Peptidomimetics & Conjugation: Used to synthesize peptide analogs where the alkyne group enables site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Chemical Biology Probes: Serves as a building block for creating activity-based probes and affinity tags to study protein function and interactions.
• Material Science: Potential monomer or cross-linker in the development of specialized polymers with tailored properties.
• Agrochemical Research: Intermediate in the synthesis of novel compounds with potential biological activity for crop protection.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and asymmetric catalysis.

Basic Information

Product Name	4-Pentynoicacid,2-Amino-2-Methyl-,Methylester,(2S)-(9Ci)
CAS No.	88820-88-6
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	(2S)-2-Amino-2-methyl-4-pentynoic acid methyl ester; Methyl (2S)-2-amino-2-methyl-4-pentynoate; L-2-Amino-2-methyl-4-pentynoic acid methyl ester; 2-Amino-2-methyl-4-pentynoic acid methyl ester, (S)-; 4-Pentynoic acid, 2-amino-2-methyl-, methyl ester, (2S)-; 2-Methyl-2-(aminomethyl)but-3-ynoic acid methyl ester (S-enantiomer)
EINECS	Contact for details

Quality Control

Our production of 4-Pentynoicacid,2-Amino-2-Methyl-,Methylester,(2S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.