Description

(S)-4-Bromo-3-Hydroxy-Butyric Acid Methyl Ester is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. This compound is valued for its defined stereochemistry, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of statin drugs (cholesterol-lowering agents) and other bioactive molecules.
• Asymmetric Synthesis: Used as a precursor for introducing the (S)-4-bromo-3-hydroxybutyryl moiety in catalytic asymmetric reactions.
• Agrochemical Research: Serves as a building block for developing chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-4-Bromo-3-Hydroxy-Butyric Acid Methyl Ester
CAS No.	88759-56-2
Molecular Formula	C5H9BrO3
Molecular Weight	197.03 g/mol
Synonyms	(S)-Methyl 4-Bromo-3-hydroxybutyrate; (S)-4-Bromo-3-hydroxybutanoic acid methyl ester; Methyl (S)-(-)-4-bromo-3-hydroxybutyrate; (3S)-4-Bromo-3-hydroxybutyric acid methyl ester; (S)-BHBM; (S)-BHBME; (S)-4-Bromo-3-hydroxybutyrate methyl ester; (S)-Methyl 4-bromo-3-hydroxybutanoate
EINECS	Contact for details

Quality Control

Our (S)-4-Bromo-3-Hydroxy-Butyric Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality management system supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.