Description

Ethyl 3-{[(tert-Butoxy)Carbonyl]Amino}Propanoate is a high-purity, protected amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive handle for constructing complex peptide and small molecule architectures while protecting the amine functionality. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of peptide-based drugs and complex organic molecules with potential therapeutic activity.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a Boc-protected β-alanine derivative for introducing specific structural motifs.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines, enabling selective reactions in complex synthetic sequences.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed in the synthesis of probes, inhibitors, and other tools for studying biological processes and target validation.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents and specialty fine chemicals.

Basic Information

Product Name	Ethyl 3-{[(tert-Butoxy)Carbonyl]Amino}Propanoate
CAS No.	88574-53-2
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	Ethyl 3-[(tert-Butoxycarbonyl)amino]propanoate; Ethyl 3-(Boc-amino)propionate; Boc-β-Ala-OEt; N-Boc-β-alanine ethyl ester; 3-[(tert-Butoxycarbonyl)amino]propionic Acid Ethyl Ester; N-(tert-Butoxycarbonyl)-β-alanine Ethyl Ester; Ethyl N-Boc-3-aminopropanoate; β-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-{[(tert-Butoxy)Carbonyl]Amino}Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring material suitability for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.