Description

(1S,2R,5E,9R)-6,10,10-Trimethylspiro[Bicyclo[7.2.0]Undec-5-Ene-2,2'-Oxirane] is a high-purity, structurally complex spirocyclic epoxide compound. This molecule is valued for its unique three-dimensional framework and reactive oxirane functionality, making it a critical advanced intermediate in sophisticated organic syntheses. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in steroidal or terpenoid-based drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its complex structure can contribute to unique biological activity.
• Fragrance & Flavor Chemistry: Acts as a precursor for high-value aroma chemicals, leveraging its terpene-derived backbone to create complex, natural-identical scent molecules.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing specialty polymers with tailored thermal or mechanical properties.
• Academic & Industrial R&D: Employed as a model compound in methodological studies for stereoselective synthesis and ring-opening reactions of strained epoxides.

Basic Information

Product Name	(1S,2R,5E,9R)-6,10,10-Trimethylspiro[Bicyclo[7.2.0]Undec-5-Ene-2,2'-Oxirane]
CAS No.	88395-50-0
Molecular Formula	C₁₄H₂₂O
Molecular Weight	206.32 g/mol
Synonyms	Spiro[bicyclo[7.2.0]undec-5-ene-2,2'-oxirane], 6,10,10-trimethyl-, (1S,2R,5E,9R)-; (-)-Spiro[4.5]dec-6-ene-7,10-epoxy-2,2,6-trimethyl; (1S,2R,5E,9R)-6,10,10-Trimethylspiro[4.5]dec-6-ene-7,10-epoxide; Spiroepoxide derivative of a trimethylbicycloundecene; Chiral spirocyclic epoxide intermediate.
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a strict quality management system. Each batch is characterized using advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption or degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.