Description

1,2-Cyclopropanedicarboxylic Acid, Monomethyl Ester, (1R,2R)- is a high-purity chiral building block of significant value in asymmetric synthesis. Its defined stereochemistry and functionalized cyclopropane ring make it a critical intermediate for constructing complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors, antiviral agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the specific stereochemistry of the cyclopropane moiety is crucial for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of chiral aroma chemicals and specialty flavors.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylic Acid, Monomethyl Ester, (1R,2R)-
CAS No.	88335-97-1
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(1R,2R)-Methyl Hydrogen Cyclopropane-1,2-dicarboxylate; (1R,2R)-1,2-Cyclopropanedicarboxylic Acid Monomethyl Ester; (1R,2R)-Cyclopropane-1,2-dicarboxylic Acid Monomethyl Ester; (1R,2R)-Methyl 1,2-Cyclopropanedicarboxylate; (1R,2R)-Methyl Cyclopropane-1,2-dicarboxylate; (1R,2R)-Monomethyl Cyclopropane-1,2-dicarboxylate; (1R,2R)-Monomethyl 1,2-Cyclopropanedicarboxylate; (1R,2R)-trans-Cyclopropane-1,2-dicarboxylic Acid Monomethyl Ester
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylic Acid, Monomethyl Ester, (1R,2R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The product is sensitive to strong bases and should be kept away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.