Description

(1S,2R)-2-(Methoxycarbonyl)-Cyclohexane-Carboxylic Acid is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound matters because its defined stereochemistry provides a critical scaffold for constructing complex, biologically active molecules with high enantiomeric purity. Pharmaceutical R&D and fine chemical manufacturers need it for the development of advanced intermediates in active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Research: Employed in academic and industrial laboratories for methodological development in stereoselective organic synthesis.
• Peptidomimetic Chemistry: Utilized to introduce constrained cyclohexane motifs into peptide analogs to modulate biological activity and stability.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral or structural properties.

Basic Information

Product Name	(1S,2R)-2-(Methoxycarbonyl)-Cyclohexane-Carboxylic Acid
CAS No.	88335-92-6
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1S,2R)-2-(Methoxycarbonyl)cyclohexanecarboxylic acid; (1S,2R)-Cyclohexane-1-carboxylic acid-2-carboxylic acid methyl ester; (-)-(1S,2R)-2-Carbomethoxycyclohexanecarboxylic acid; Methyl (1S,2R)-2-carboxycyclohexanecarboxylate; (1S,2R)-1,2-Cyclohexanedicarboxylic acid 2-methyl ester; trans-2-(Methoxycarbonyl)cyclohexanecarboxylic acid (specific stereoisomer)
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-(Methoxycarbonyl)-Cyclohexane-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and standard purity assays. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.