Description

2-Amino-5-Nitronicotinic Acid Ethyl Ester is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), specialty dyes, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex nitrogen-containing heterocycles for potential drug candidates, including kinase inhibitors and antibacterial agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its nitropyridine structure.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and pigments with specific light-fastness properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and synthesizing novel chemical entities.
• Material Science: Investigated as a monomer or functional additive in the development of advanced polymers and coordination complexes.

Basic Information

Product Name	2-Amino-5-Nitronicotinic Acid Ethyl Ester
CAS No.	88312-65-6
Molecular Formula	C8H9N3O4
Molecular Weight	211.18 g/mol
Synonyms	Ethyl 2-Amino-5-nitronicotinate; 5-Nitro-2-aminonicotinic Acid Ethyl Ester; 2-Amino-5-nitro-3-pyridinecarboxylic Acid Ethyl Ester; Ethyl 2-Amino-5-nitro-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 2-amino-5-nitro-, ethyl ester; 88312-65-6; 2-Amino-5-nitropyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Nitronicotinic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). The COA includes data from advanced analytical techniques such as HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.