Description

3-Pyridinecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a versatile pyridine derivative and a key synthetic intermediate in organic chemistry. Its value lies in its bifunctional reactivity, featuring both an ester and an acid chloride group, making it a crucial building block for constructing complex heterocyclic systems. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing nicotinic acid or pyridine-based pharmacophores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, insecticides, and fungicides that require specific pyridine ring structures.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the pyridine unit modifies electronic properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and activity-based probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	88234-87-1
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	2-(Chlorocarbonyl)nicotinic acid methyl ester; Methyl 2-(chlorocarbonyl)nicotinate; Methyl 2-(chloroformyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester; 2-Carbomethoxy nicotinoyl chloride; Nicotinic acid, 2-(chlorocarbonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.