Description

(1'R,2R,4S,5'R)-3,4-Dihydro-5,7-Dihydroxy-6',6'-Dimethyl-4-(2-Methylpropyl)Spiro[2H-1-Benzopyran-2,2'-Bicyclo[3.1.1]Heptane]-6,8-Dicarbaldehyde is a high-purity, complex spirocyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate molecular architecture, featuring a benzopyran fused to a bicyclo[3.1.1]heptane system, makes it a valuable chiral building block and a potential precursor for novel active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions due to its rigid, three-dimensional structure.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization programs.
• Fine Chemical Production: Acts as a building block for the synthesis of complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Development: Investigated as a potential intermediate for novel pesticides or herbicides with unique modes of action.
• Material Science: Explored for the development of advanced organic materials, such as chiral dopants for liquid crystals or components for organic electronics.

Basic Information

Item	Details
Product Name	(1'R,2R,4S,5'R)-3,4-Dihydro-5,7-Dihydroxy-6',6'-Dimethyl-4-(2-Methylpropyl)Spiro[2H-1-Benzopyran-2,2'-Bicyclo[3.1.1]Heptane]-6,8-Dicarbaldehyde
CAS No.	88197-30-2
Molecular Formula	C24H30O6
Molecular Weight	414.49 g/mol
Synonyms	6',6'-Dimethyl-4-(2-methylpropyl)spiro[2H-1-benzopyran-2,2'-bicyclo[3.1.1]heptane]-3,4-dihydro-5,7-diol-6,8-dicarbaldehyde; Spiro[2H-1-benzopyran-2,2'-bicyclo[3.1.1]heptane]-6,8-dicarbaldehyde derivative; CAS 88197-30-2; (1'R,2R,4S,5'R)-rel-3,4-Dihydro-5,7-dihydroxy-6',6'-dimethyl-4-(2-methylpropyl)-; Spirocyclic benzopyran dicarbaldehyde
EINECS	Contact for details

Quality Control

Our (1'R,2R,4S,5'R)-3,4-Dihydro-5,7-Dihydroxy-6',6'-Dimethyl-4-(2-Methylpropyl)Spiro[2H-1-Benzopyran-2,2'-Bicyclo[3.1.1]Heptane]-6,8-Dicarbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure consistent identity, purity, and performance for critical R&D applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic results (NMR, MS) are provided to guarantee full traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.