Description

Haloxazolam is a high-purity benzodiazepine derivative, recognized for its specific pharmacological profile and utility in advanced research and development. This compound is of significant interest for its role in the study of central nervous system (CNS) activity and receptor binding mechanisms. It serves as a critical intermediate and reference standard for pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions focused on neuropharmacology.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel benzodiazepine-class compounds.
• Analytical Reference Material: Used as a high-purity standard in HPLC, GC-MS, and other chromatographic methods for method development, validation, and quality control testing.
• Biochemical Research: Employed in in vitro studies to investigate GABAA receptor subtypes, binding affinity, and pharmacological effects.
• Academic & Clinical Studies: Utilized in university and institutional research projects exploring sedative-hypnotic mechanisms and structure-activity relationships (SAR).
• Chemical Synthesis: Acts as a specialized building block for the preparation of more complex molecules in medicinal chemistry programs.

Basic Information

Product Name	Haloxazolam
CAS No.	88195-91-9
Molecular Formula	C17H14BrFN2O2
Molecular Weight	377.21 g/mol
Synonyms	10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one; CS-430; Haloxazolamum; Haloxazolam [USAN:INN]; Haloxazolam (JAN/USAN/INN); UNII-4QWG443N42; 4QWG443N42
EINECS	Contact for details

Quality Control

Our Haloxazolam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities, to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with the agreed specification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.